Knowing Your Dosage – Marijuana Stocks
What’s In YOUR….Edible?
The now famous line, “What’s in your wallet?” can certainly apply to the cannabis industry. But before we try to figure out what’s in your edible, we need to figure out what’s in your cannabis. Below is a summary of foreign compounds found in cannabis, and the reasoning behind why certain manufacturers are truly unable to quantify the exact dosage and purity in their respective edibles.
Cyanide, Anyone? As per Steep Hill, a laboratory testing entity, over 80% of the cannabis tested at their Berkley lab was contaminated, and most likely will not pass the State of California testing requirements beginning January 1st, 2018. The reason? The amount of harmful, toxic chemicals that have been used for years to ‘help’ grow a ‘healthy’ harvest. Myclobutanil, Trifloxystrobin, Paclobutrazol, Bifenazate, and Bifenthrin are some of the more common chemicals used for growing, with Myclobutanil being the leader. In fact, according to various reports, up to 66% of cannabis grown in California contains Myclobutanil. So, what is Myclobutanil?
Myclobutanil is the active ingredient in several brands of pesticides including Eagle 20EW. As a systemic chemical, Myclobutanil cannot be removed by washing treated crops. The final remaining residual levels before harvesting may vary greatly, and will depend on many factors, including the last application before harvest. The bottom line is that, more likely than not, if Myclobutanil was applied during the growing process, then you’re going to consume some Myclobutanil. And, consuming any of it means you’re consuming Hydrogen Cyanide. In short, Myclobutanil is stable at room temperature, but releases highly toxic gases if heated past its boiling point of 205 degrees C. Disposable butane lighters used to ignite cannabis produce temperatures in excess of 450 degrees C. The result? Release of Hydrogen Cyanide – one of the most toxic, harmful and deadly compounds known to mankind. In fact, Hydrogen Cyanide is a Schedule 3 toxic chemical under the Chemicals Weapon Convention when heat is applied. For example, when you light up your cannabis.
“Dosage is everything” – Paracelsus. Philippus Aureolus (a/k/a Paracelsus), the great German-Swiss physician and alchemist who established the role of chemistry in medicine in the late 15th century, had it right. Dosage is everything. For example, you have an mmj brownie or cookie similar to last night, but 30 minutes later you’re not feeling a thing. Nothing. Or worse, the unexpected amount of THC hitting your system causes you to hunt for the nearest couch or bed. The culprit? The inability of an edible’s manufacturer to accurately and consistently quantify the precise amount of active cannabis ingredients in each cookie.
Variables in the manufacturing process include, but are not limited, to the quality of the plant, the reaction of the plant’s natural and foreign chemicals when heated, combining the plant with other ingredients, and the external environment (air temperature, humidity), as well as the biphasic effect. Cannabis compounds have biphasic properties, which means that low and high dosages of the same substance can produce opposite effects. Combining the various factors together means it’s extremely difficult during the manufacturing process to constantly and consistently create an equal dosage of a specific cannabis compound in edibles on a regular basis. This problem is exacerbated when scaling the product to meet consumer demands.
Consistent Dosage Exists. CannaStrips™ are not edibles. In fact, they’re so unique and effective, they truly belong in a class by themselves. They’re discreet, odorless, wildly effective and relatively inexpensive. Especially when you compare the costs associated with purchasing the same amount of active ingredients such as CBD or THC in any other cannabis related product. More specifically, CannaStrip™ are a sub-lingual oral strip, similar to a breath strips, are not only a safer, healthier option to smoking, but also a new way to accurately meter the dosage and assure the purity of the product. Unlike edibles, Lifestyle Delivery Systems’ has a unique method for delivering nano-encapsulated biological molecules of therapeutic value systemically – directly across mucous membranes – in order to achieve ease of administration, compliance, dose repeatability and improved bioavailability. In addition, CannaStripsTM proprietary process involves reducing all elements in its formulation to a micro particulate size and homogenizing the mixture into a lipid encapsulation. This allows the active cannabinoids and terpenes to enter the bloodstream quickly through the buccal membrane of the mouth and remain in the blood stream until receptors in the body are available.
The entire plant and all of its synergistic components of cannabinoids, terpenes, terpenoids, flavonoids and other entities are used in the formulation of CannaStrips™. The combination of cannabinoids, terpenes and terpenoids found in cannabis plants cause an “entourage effect,” which means that the impact of the whole cannabis plant is extremely beneficial. This may explain why so many people seem to get better results from using whole plant extract compared to highly distilled versions of pure THC or pure CBD and CBN.
Get your Dosage (and purity) Right, or Go Home. The State of California rules and regulations stipulate extractions using CO2, or a volatile solvent, using a closed-loop system. The State has a variety of other rules and regulations pertaining to extraction, but the bottom line is that the State is trying to get clean biomass into the system.
“Though the State of California does allow for a small variance when testing for products, our recently tested fresh frozen biomass had absolutely no contaminants. Zero. This is the goal at Lifestyle Delivery Systems that we’ll continue to strive for. With our cutting-edge technology and the fact that the active ingredients of our CannaStripsTM are literally in a patient’s bloodstream in less than two minutes, it’s critical we have clean, unaltered biomass,” states Brad Eckenweiler, CEO of Lifestyle Delivery Systems. He cautions, “We’re seeing more compromised flower and oils in the marketplace today and we anticipate that will continue until the end of the year. A lot of groups that have failed to follow municipal and state protocol are dumping their goods because in about a month, the value of those same goods will probably be negligible at best.”
“We hear it from investors in California regularly. They cannot identify any other company that has created the complete vertically-integrated system like LDS. From our eight isogenic rooms, agricultural nursery, cultivation, extraction and distillation, to our state-of-the-art laboratory, we think we’ve created an ecosystem that differentiates us from everyone else. We look forward to operating in a state with 39 million residents and 251 million annual visitors.”
Sources: Greenrushdaily.com, ColoradoGreenLab.com, ProjectCBD.org, CA.Cannabis.Gov